Elevated proprotein convertase subtilisin/kexin type 9 (PCSK9) levels have been associated with adverse outcomes in patients hospitalized for sepsis. PCSK9 loss-of-function (LOF) variants area ...

A new case-control genetic study is reassuring in finding no association between a genetic proxy for pharmacologic PCSK9 inhibition and either heart failure or adverse cardiac remodeling in a large ...

How does PCSK9 function and what is the impact of this protein on cardiovascular disease? A research team coordinated by Dr. Nabil G. Seidah, researcher at the IRCM and at Université de Montréal, has ...

Please provide your email address to receive an email when new articles are posted on . “PCSK9 inhibition, as modeled via genetic Mendelian randomization methods, has a neutral cognitive profile,” ...

Verve is targeting patients with genetically-driven high cholesterol levels, and they are making a single A-to-G change in the gene for the PCSK9 protein. Verve announced their results yesterday, and ...

A protein called PCSK9 determines how pancreatic cancer cells metastasize to different parts of the body. Scientists at UC San Francisco have discovered how pancreatic cancer cells thrive in the lungs ...

MANNHEIM, Germany—Response to treatment is highly variable with the investigational PCSK9 inhibitor lerodalcibep (LIB Therapeutics), as well as with evolocumab (Repatha; Amgen), in patients who have ...

DALLAS – April 17, 2009 – Researchers at UT Southwestern Medical Center have found that a protein responsible for regulating "bad" cholesterol in the blood works almost exclusively outside cells, ...